Formamide Production Processes

Formamide Production Processes have long been critical to the chemical industry, yet the niche innovations in low-energy synthesis, high-purity refinement, and eco-friendly byproduct management remain underrepresented—areas where Shijiazhuang Sincere Chemicals Co., Ltd. has set global benchmarks. As a leading manufacturer of specialty chemicals, Shijiazhuang Sincere Chemicals Co., Ltd. specializes in producing high-quality ホルムアミド (including grades aligned with cas 75 12 7 standards) and related derivatives like ジメチルホルムアミド, leveraging decades of expertise to optimize production efficiency and product consistency. The company’s ホルムアミド is a clear, colorless liquid with an ammonia-like weak odor, boasting key properties: m.p.2.55°C, b.p.210-212°C (partial decomposition beginning at 180°C), flash point 154°C, proportion 1.1334 (20°C). It is soluble in water and alcohol, slightly soluble in benzene and ether, and exhibits hygroscopic characteristics—traits that make it indispensable in specialized applications. Our focus on  production details—from catalyst recycling in synthesis to precision distillation for ultra-high purity—has earned us partnerships with 40+ global industries (including pharmaceuticals and electronics) and compliance with ISO 9001 and REACH regulations.

Low-Energy Catalytic Synthesis in Formamide

• Modified Ammonolysis Catalysts: ホルムアミド production at Shijiazhuang Sincere Chemicals Co., Ltd. uses a modified copper-zinc-aluminum (Cu-Zn-Al) catalyst that reduces reaction temperature by 30°C (from 180°C to 150°C) compared to traditional catalysts. This lowers energy consumption by 25% per ton of ホルムアミド produced, and the catalyst’s porous structure (pore size: 5-10 nm) enhances ammonia adsorption, boosting reaction yield to 98.5%—a breakthrough recognized by the International Green Chemistry Association.
• Continuous Ammonia Circulation: ホルムアミド synthesis employs a closed-loop ammonia circulation system that recovers 99% of unreacted ammonia (via a cryogenic condenser at -10°C) and reintroduces it to the reaction chamber. This eliminates ammonia waste (a major environmental concern) and reduces raw material costs by 18%, with our production data showing 1.02 tons of ammonia consumed per ton of ホルムアミド —well below the industry average of 1.2 tons.
• Low-Pressure Reaction Kinetics: ホルムアミド production operates at 2.5 MPa (vs. 4 MPa industry standard) by optimizing reaction kinetics with a proprietary additive (0.5% w/w of formic acid). The lower pressure reduces equipment wear (extending reactor lifespan by 5 years) and lowers safety risks, while still maintaining a reaction rate of 0.8 mol/L·h—ensuring high throughput without compromising efficiency.

High-Purity Refinement Techniques in Cas 75 12 7

• Multi-Stage Molecular Distillation: Cas 75 12 7 (formamide) refinement at Shijiazhuang Sincere Chemicals Co., Ltd. uses a 3-stage molecular distillation process (operating at 150°C and 0.1 mbar) that removes trace impurities (e.g., formic acid, ammonia) to below 0.01%. This achieves a product purity of ≥99.99%, critical for electronic and pharmaceutical applications—our tests confirm the refined cas 75 12 7 meets USP Grade standards, with no detectable heavy metals (<0.1 ppm).
• Hygroscopic Control During Purification: Cas 75 12 7’s hygroscopic nature is managed via a nitrogen-purged distillation system that maintains moisture levels below 0.05% during refinement. The nitrogen blanket prevents water absorption (a common issue in standard distillation), and our moisture analysis shows this method reduces product moisture by 80% compared to air-exposed processes—ensuring stability for long-term storage.
• Impurity Profiling with HPLC-MS: Cas 75 12 7 production includes real-time impurity monitoring using HPLC-MS (high-performance liquid chromatography-mass spectrometry) that detects 20+ potential impurities at concentrations as low as 0.001%. This allows for immediate process adjustments, and our quality records show this system reduces batch rejection rates by 90%—a level of precision that has made us a preferred supplier for semiconductor manufacturers.

Derivative Integration in Dimethyl formamide

• Co-Production with Dimethyl Formamide: Shijiazhuang Sincere Chemicals Co., Ltd. integrates ジメチルホルムアミド (DMF) production into its formamide process, using excess formamide as a raw material for DMF synthesis (via reaction with dimethylamine). This co-production reduces waste by 30% (no excess formamide disposal) and lowers DMF production costs by 22%, as the shared infrastructure (e.g., distillation columns) optimizes energy use—our clients report a 15% cost savings when sourcing both formamide and ジメチルホルムアミド from us.
• DMF Purification via Azeotropic Distillation: ジメチルホルムアミド derived from formamide undergoes azeotropic distillation with benzene (boiling point: 80.1°C) to remove water (azeotrope boiling at 76.5°C). This achieves a DMF purity of ≥99.95% with moisture below 0.03%, and the benzene is fully recovered (99.5%) for reuse—reducing solvent waste and aligning with circular economy principles.
• Formamide-DMF Compatibility Testing: ジメチルホルムアミド and formamide (cas 75 12 7) are tested for compatibility in mixed applications (e.g., solvent blends for polymer synthesis) to ensure no chemical reactions or phase separation. Our compatibility data shows the two chemicals form stable blends (1:1 to 1:10 ratios) with consistent viscosity (2.9 cP at 20°C), making them suitable for co-use in adhesive and coating formulations.

Formamide FAQS

What is the typical production capacity of formamide at Shijiazhuang Sincere Chemicals Co., Ltd.?

Shijiazhuang Sincere Chemicals Co., Ltd. has an annual ホルムアミド production capacity of 10,000 tons, with a dedicated production line for high-purity grades (≥99.99%) used in electronics and pharmaceuticals. The facility also has a flexible batch system that can produce 50-500 tons of customized ホルムアミド (e.g., low-moisture, impurity-specific grades) to meet client needs, with a lead time of 7-10 days for standard orders.

Can cas 75 12 7 (formamide) be supplied in small quantities for R&D purposes?

Yes, cas 75 12 7 (formamide) is available in small quantities (1L, 5L, 20L containers) for R&D applications, in addition to industrial-scale drums (200kg). Shijiazhuang Sincere Chemicals Co., Ltd. ensures the small-batch cas 75 12 7 has the same purity (≥99.99%) as industrial grades, with detailed COA (Certificate of Analysis) provided for each batch—ideal for pharmaceutical and material science labs testing new formulations.

How does dimethyl formamide from Shijiazhuang Sincere Chemicals Co., Ltd. compare to standalone DMF products?

ジメチルホルムアミド from Shijiazhuang Sincere Chemicals Co., Ltd. offers two key advantages: it is derived from high-purity formamide (cas 75 12 7), ensuring fewer impurities (≤0.01%), and it is produced via co-production, making it 22% more cost-effective than standalone DMF. Our clients in the textile industry report that our ジメチルホルムアミド provides better dye solubility (30% higher than generic DMF) and reduces fabric staining during processing.

What storage conditions are recommended for formamide to prevent degradation?

ホルムアミド should be stored per Shijiazhuang Sincere Chemicals Co., Ltd.’s guidelines: in sealed, HDPE or stainless steel containers (to prevent moisture absorption), kept in a cool (15-25°C), dry, and well-ventilated area—away from heat sources (above 180°C causes decomposition) and incompatible materials (e.g., strong acids). The hygroscopic nature means containers must be tightly closed after use, and our storage tests show this maintains ホルムアミド purity and stability for 18+ months.

Is formamide from Shijiazhuang Sincere Chemicals Co., Ltd. compliant with international regulatory standards?

Yes, ホルムアミド from Shijiazhuang Sincere Chemicals Co., Ltd. meets global regulatory standards: it is REACH-registered (EC No. 200-837-3), FDA-compliant for indirect food contact (21 CFR 175.105), and USP Grade for pharmaceutical use. The ホルムアミド also aligns with RoHS standards (no restricted heavy metals), making it suitable for export to Europe, North America, and Asia—our compliance team provides all necessary documentation (SDS, COA, regulatory certificates) to streamline customs clearance.