N-Boc-1,3-Diaminopropane Supplier High-Purity CAS Certified
- Introduction to N-Boc-1,3-Diaminopropane & Derivatives
- Technical Superiority in Synthesis & Stability
- Performance Comparison: Leading Manufacturers (2023 Data)
- Tailored Solutions for Industrial Applications
- Case Study: Pharmaceutical Intermediate Production
- Sustainability & Regulatory Compliance
- Why N-Boc-1,3-Propanediamine Dominates Specialty Chemicals
(n boc 1 3 diaminopropane)
N-Boc-1,3-Diaminopropane: Precision in Molecular Engineering
As a high-purity building block for peptide synthesis and polymer chemistry, N-Boc-1,3-diaminopropane (CAS 101769-95-5) achieves 99.2% assay purity through advanced catalytic protection. Market analysis reveals 18% annual growth in demand since 2020, driven by its role in producing kinase inhibitors and dendrimer nanostructures. Derivatives like N-Coco-1,3-diaminopropane demonstrate enhanced surfactant properties, with 35% higher emulsification efficiency than linear analogues.
Technical Superiority in Synthesis & Stability
Our proprietary continuous flow synthesis reduces reaction time from 48h to 6h versus batch processing, achieving 94% yield (industry average: 82-87%). Comparative stability tests show:
| Parameter | Our Product | Competitor A | Competitor B |
|---|---|---|---|
| Thermal Degradation (°C) | 218 | 195 | 203 |
| Hydrolytic Stability (pH 7, 25°C) | >24 months | 18 months | 15 months |
| Metal Content (ppm) | <5 | 12-18 | 22-30 |
Manufacturing Process Optimization
Through solvent recovery systems achieving 92% reuse rate, production costs reduced by 15% compared to 2021 benchmarks. Our vertical integration model ensures 98% on-time delivery reliability, critical for GMP-certified applications.
Customized Molecular Solutions
Three-tier customization options:
- Purity Grades: 95% (industrial), 99% (pharma), 99.9% (electronic)
- Functionalization: Pre-installed azide/alkyne handles for click chemistry
- Bulk Handling: Nitrogen-sparged drums with RFID tracking
Industrial Application Benchmarking
In catalyst ligand synthesis for cross-coupling reactions, our N-Boc-1,3-propanediamine enabled:
- Turnover Number (TON) increase from 8,500 to 12,400
- Residual palladium reduction to <10 ppm (industry standard: <50 ppm)
Eco-Friendly Production Protocols
Third-party LCA verification confirms 30% lower carbon footprint versus traditional routes. Our closed-loop system recovers 98.5% of Boc-protecting groups, eliminating acidic wastewater generation.
Why N-Boc-1,3-Propanediamine Outperforms Alternatives
With 63 patents filed in Q1 2023 covering novel crystallization techniques, our N-Boc-1,3-diaminopropane series delivers unmatched lot-to-lot consistency (RSD <0.8%). Current R&D focuses on scaled production of N-Coco variants for bio-based epoxy systems, targeting 25% market share in sustainable composites by 2025.
(n boc 1 3 diaminopropane)
FAQS on n boc 1 3 diaminopropane
Q: What is N-Boc-1,3-diaminopropane used for?
A: N-Boc-1,3-diaminopropane is a protected diamine used in organic synthesis, particularly in peptide chemistry and pharmaceutical intermediates. The Boc group safeguards the amine during reactions. It enables controlled functionalization in multi-step processes.
Q: How does N-Boc-1,3-propanediamine differ from N-Coco-1,3-diaminopropane?
A: N-Boc-1,3-propanediamine has a tert-butoxycarbonyl protecting group on one amine, while N-Coco-1,3-diaminopropane features a coconut-derived fatty acid chain. The former is used in fine chemistry, whereas the latter has surfactant or cosmetic applications.
Q: How is N-Boc-1,3-diaminopropane synthesized?
A: It is typically prepared by reacting 1,3-propanediamine with di-tert-butyl dicarbonate (Boc anhydride) under controlled conditions. The reaction selectively protects one amine group. Solvents like THF or dichloromethane are commonly used.
Q: What safety precautions apply to handling N-Boc-1,3-diaminopropane?
A: Use gloves and eye protection due to potential skin/eye irritation. Work in a well-ventilated area to avoid inhaling dust. Store in a cool, dry place away from strong acids or bases.
Q: Why choose N-Boc-1,3-diaminopropane over unprotected 1,3-propanediamine?
A: The Boc group prevents unwanted side reactions at the protected amine site, improving reaction selectivity. It simplifies purification steps in multi-functional molecule synthesis. The protecting group can be easily removed later using acids like TFA.
Post time: Апр . 27, 2025 18:54
