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Phenyl Dichlorophosphate: Industry Trends, Specifications, and Application Insights (2024 Deep Dive)

1. Global Phenyl Dichlorophosphate Market & Industry Trends

Phenyl Dichlorophosphate (C₆H₅OP(O)Cl₂, CAS 770-12-7) is a vital organophosphorus intermediate, widely utilized as a phosphorylating, chlorinating, and flame-retardant reagent in advanced chemical syntheses. According to Phenyl Dichlorophosphate market reports by MarketWatch and Statista, the global demand for high-purity organophosphates is expected to grow at a CAGR of 6.1% from 2023 to 2028, driven by innovation in pharmaceuticals, agrochemicals, polymer additives, and flame retardant solutions.

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      Recent advances in Phenyl Dichlorophosphate manufacturing—such as continuous flow chlorination, automated reactor control, and stringent ISO 9001/ISO 14001 certifications—consistently improve product quality, batch consistency, and safety compliance across top-tier suppliers in China, Europe, and North America.
    

2. Phenyl Dichlorophosphate Technical Specification & Industry Data

Key Physical & Chemical Characteristics

Parameter	Specification / Typical Value	Test Method	Industrial Significance
Chemical Formula	C₆H₅OPOCl₂	N/A	Denotes primary molecular structure
Appearance	Colorless to pale yellow transparent liquid	Visual	Visual inspection for purity, batch consistency
Purity (%)	≥ 99.0	GC, HPLC	Ensures reactivity, suitability for high-value syntheses
Phosphorus Content (%)	15.0 - 15.4	Titrimetric	Supports product identification and batch tracking
Chloride Content (%)	< 0.5	Silver nitrate titration	Controls for corrosion/reactivity risks
Boiling Point	245 - 250 °C	ASTM D1120	Critical for safe storage/transport, process design
Melting Point	−17 °C	ASTM E324	Relevant for handling, low-temp transport
Water Content (%)	< 0.1	Karl Fischer	Reduces hydrolysis in storage, guarantees shelf life
Flash Point	107 °C	ISO 3679	Guides on-site safety protocols
Solubility	Slightly soluble in water, miscible with organics	Solubility test	Determines compatibility for blends/formulations
Toxicity (LD50, rat, oral)	~120 mg/kg	OECD 401	For risk assessment and labeling compliance

All shipments of Phenyl Dichlorophosphate from leading suppliers comply with ISO 9001 (Quality Management System) and ISO 14001 (Environmental Management) standards, delivering batch-to-batch reproducibility and environmental safety.

3. Phenyl Dichlorophosphate Manufacturing Process (Technological Flowchart & Standards)

The synthesis of Phenyl Dichlorophosphate typically follows a chlorination route, optimized for high selectivity and purity:

▲ Process Flow Diagram: From phenol + phosphorus oxychloride (POCl₃) → reaction → phase separation → distillation → product purification.

Raw Materials: Phenol (C₆H₅OH), Phosphoryl chloride (POCl₃), catalytic acid scavenger.
Reactor Technology: Corrosion-resistant glass-lined or stainless steel reactor system ensures product integrity, certified to CE/ANSI standards.
Chlorination Control: Automated dosing with continuous stirring and temperature feedback for high purity.
Phase Separation & Purification: Multi-stage phase separation, fine vacuum distillation for residuals removal & consistent purity.
Quality Testing: Inline GC/IR for composition analysis, batch QC per ISO 9001 and ANSI/ASQ Z1.4 standards.

Material & Construction Advantages: Components such as reactor impellers, piping, and valves are made from specialty alloys or acid-resistant grades (SS316L, PTFE lining) for prolonged service life (>10 years) and minimization of corrosion-induced contamination, indispensable for reliability in industrial operation.

4. Application Scenarios & Technical Advantages of Phenyl Dichlorophosphate

Pharmaceuticals: Acts as a phosphorylating agent in the synthesis of prodrugs, nucleotide analogs, and enzyme inhibitors, with high selectivity and minimal by-products.
Agrochemicals: Serves as a core intermediate to prepare organophosphorus pesticides, insecticides, and herbicides; supports controlled release and increased crop yield.
Polymer Additives: Used in flame-retardant and plasticizer manufacture; imparts enhanced thermal and hydrolysis resistance.
Flame Retardants (Electronics, Transportation): Delivers halogen-free fire protection in insulation, cables, fabrics, and automotive foams with proven efficiency (up to 40% reduction in flame propagation).
Industrial Catalysts: Applied as a chlorinating & phosphorylating agent in transition-metal catalysis for specialty process chemicals.
Other Industries: Phenyl Dichlorophosphate is also used in metallurgy (as a passivating agent) and in advanced surfactant/solvent production for specialty fluids.

      User Experience: Feedback from multinational clients in the electronics (PCB), pharma synthesis, and agriculture sectors highlights exceptional process yields (98–99%) and reduced maintenance costs (20–30% lower) due to the superior anti-corrosion properties of equipment utilizing Phenyl Dichlorophosphate feedstock.
    

5. Manufacturer Comparison: Key Players in the Phenyl Dichlorophosphate Supply Chain

Below is an overview of leading manufacturers, summarized through technical competitiveness, certifications, and after-sales service capabilities:

Vendor	Origin	Purity (%)	Certifications	Production Capacity (MT/year)	Customization	Lead Time
Sincere Chemicals	China	≥99.0	ISO 9001, ISO 14001	1200	Yes	12-18 Days
Valence Labs	USA	98.5–99.2	GMP, ISO	600	No	21-30 Days
Lucent Organics	India	≥99.0	ISO 9001, REACH	900	Yes	16-25 Days
PhosPharm Europe	Germany	98.0–99.0	ISO, FDA	750	No	18-25 Days

      Sincere Chemicals leads the pack with the highest capacity, fastest response for custom specifications, and strictest environmental compliance (ISO 14001). Their technical service and customer support operate 24/7.
    

6. Custom Solutions & Real-World Cases: Phenyl Dichlorophosphate Adaptability

Pharmaceutical Process Customization: Custom design for high-purity, ultra-low moisture (Phenyl Dichlorophosphate, delivered to a leading Asian pharma API plant—result: yield increased by 3.5%, downstream side-product impurities cut by 72%.
Flame Retardant Application (Automotive OEM): Joint R&D with a European auto parts supplier to optimize polymer flame retardancy for e-vehicle battery insulation. Field tests: Oxygen Index 32.5% (vs. 28% norm), 25% increase in fire resistance.
Pipelines in Water-Treatment: Integrated anti-corrosion material selection for Phenyl Dichlorophosphate dosing equipment (PTFE, SS316L) in large-scale waterworks, resulting in 12-year mean time between failures (MTBF), 90% uptime over a decade.
Remote QC Integration: IoT-based sensor installation (inline GC/FTIR) for continuous purity and by-product monitoring—reduced batch deviation to below 0.9% in 2023-2024.

      Experience-Driven Innovation: All custom projects are documented with step-by-step field data, QHSE reports, and third-party certifications (SGS, Intertek) on request.
    

7. Data Visualization: Technical Benchmarking & Trends

8. Phenyl Dichlorophosphate Professional FAQ

Q1: What is the chemical structure and key functional group of Phenyl Dichlorophosphate?

A: Phenyl Dichlorophosphate is a phosphorus oxychloride esterified with a phenyl group, formula C₆H₅OPOCl₂. The core feature is the P=O and P–Cl bonds, making it an active phosphorylating agent for organic synthesis.

Q2: What are the typical purity grades available and their impact on end use?

A: Industrial grades are usually 97–99%, while reagent/pharma grades exceed 99.5%. For pharma APIs and electronics, high purity is essential for process yield and product safety.

Q3: What materials are recommended for storage and handling?

A: Recommend using PTFE, SS316L, or glass-lined vessels, as Phenyl Dichlorophosphate hydrolyzes with water and attacks ordinary steels. Packaging is typically in HDPE or fluoropolymer drums.

Q4: What are the main analytical methods for quality control?

A: Main tests include GC (purity), FTIR (structure confirmation), water content (Karl Fischer), and non-volatile residue; advanced lots may also be batch-traceable by HPLC and NMR.

Q5: Which international certifications should a reputable supplier hold?

A: Internationally, ISO 9001 (quality), ISO 14001 (environmental), and for specialty use, REACH registration or FDA certification if used in pharma.

Q6: How is Phenyl Dichlorophosphate supplied and what are common packaging specs?

A: Bulk: 200kg HDPE drums or 1000L IBCs, nitrogen-purged, UN-approved. Pharma/lab grade: 10–50kg fluoropolymer drums or sealed ampoules upon request.

Q7: What are typical delivery times and associated logistics standards?

A: Stock goods ship in 7–12 days; custom lots 14–21 days worldwide by sea/air, with full DG certification, MSDS in GHS format, and GPS tracking. All logistics adhere to IMDG and IATA standards.

9. Delivery, Warranty & Customer Support

Standard Lead Time: Stock: 7–12 days; Custom specs (ultra-high purity, specialty packaging): 12–18 days.
Warranty: All Phenyl Dichlorophosphate batches guaranteed >99% purity for 12 months upon factory dispatch, with batch-level CoA.
After-Sales Support: 24/7 hotline, dedicated application engineers for troubleshooting, process optimization, and EHS consulting.
Technical Documentation: Real-time access to CoA, MSDS, and TDS for each shipment; bilingual support in English, French, Chinese.
On-Site Audits: GMP or ISO-compliant audits available by appointment for bulk clients.
Return & Replacement Policy: 100% refund on out-of-spec batches within 7 working days; free technical replacement for critical production issues.