N-Methylformamide Supplier | High-Purity AI Solvent
N-Methylformamide (NMF) is a high-purity and versatile organic solvent intensively used across petrochemical, pharmaceutical, polymer, and metallurgy industries. With the continuous evolution of global chemical manufacturing standards, demand for top-grade N-Methylformamide is surging, owing to its unique physicochemical attributes and high compatibility with industry compliance requirements such as ISO 9001:2015 and FDA references [1]. This article explores the latest trends, product specifications, competitive technology insights, manufacturing process, and real-life application cases involving N-Methylformamide.
Market Trends & Industrial Demand for N-Methylformamide
- The global N-Methylformamide market is expected to grow at a CAGR of 5.6% (2023-2029), reaching USD 820 million by 2029[2].
- Accelerated adoption in fine chemicals, agrochemicals, and new energy battery manufacturing.
- Increasing focus on ultra-purity, sustainability, and compliance with REACH, ISO, and environmental standards.
- Key players: Sincere Chemicals, BASF, Eastman, Mitsubishi Gas Chemical, Balaji Amines.
- Asia-Pacific dominates global supply and demand, led by China and India.

Industry Citation: Source: Global Market Insights
Technical Specification Table of N-Methylformamide
Parameter | Unit | Typical Value | Test Method |
---|---|---|---|
Purity | % (w/w) | ≥ 99.5 | Gas Chromatography (ISO 17025) |
Water Content | % (w/w) | ≤ 0.1 | Karl Fischer Titration (DIN EN ISO 760) |
Color (APHA) | Hazen units | ≤ 10 | ASTM D1209 |
Acidity (as HCOOH) | mg/kg | ≤ 25 | ISO 6353 |
Boiling Point | °C | 199 | ISO 918 |
Density (20°C) | g/cm3 | 0.999 | ISO 1183 |
Refractive Index n20D | - | 1.4270 | ISO 5661 |
Flash Point | °C | 91 | ISO 3679 |
Storage Stability | Months | > 12 | ISO 1042 |
Manufacturing Process Flow of N-Methylformamide

- Raw Material Input: Methanol + Formamide.
- Catalytic Methylation: React in stainless steel Catalytic Reactor (ISO 9001 process control). ⬇
- Distillation & Rectification: Multi-stage fractional distillation to achieve high-purity separation.⬇
- Purity Control: On-line gas chromatography and Karl Fischer titration for water/organic residues.⬇
- Stabilization & Storage: ISO compliant tank storage for ensured shelf-life stability.
- Raw material selection: Sourced per ISO 9001:2015 standards.
- Corrosion-resistant process equipment ensures zero contamination, improved lifespan, and compliance with GMP/FDA.
- Advanced CNC machining for reactor/column manufacturing provides high dimension accuracy and longevity.
- Full-process traceability and in-process monitoring by digital instrumentation (TÜV-CE certified).
Competitive Comparison: N-Methylformamide Suppliers
Manufacturer | Main Grade | Purity (%) | Certification | Lead Time (Days) | Annual Output (Tons) |
---|---|---|---|---|---|
Sincere Chemicals | Pharma / Electronic | 99.5 – 99.9 | ISO 9001, FDA ref | 7 - 15 | 32,000 |
BASF | Industrial | 99.5 | ISO 9001 | 14 - 21 | 20,000 |
Eastman | Standard | 99.2 – 99.5 | ISO 9001 | 20+ | 16,800 |
MGC (Japan) | High-purity | 99.7 | ISO 9001/14001 | 19 | 8,900 |
Balaji Amines | Commodity | 99.0 – 99.5 | REACH | 18 | 7,300 |
Key Advantages & Industry Certifications
- Exceptional Purity: Ensures high selectivity and yield in polymerization, pharmaceuticals, and agrochemical synthesis.
- Regulatory Compliance: Full adherence to ISO 9001:2015, FDA reference, REACH, RoHS, and GMP for pharma/food applications.
- Resistant to Corrosive Degradation: Alkali and acid-resistant vessel design prevents product contamination and ensures >99% batch reproducibility.
- Longevity & Stability: Minimum 12-month shelf life with no functional decomposition under recommended storage (20-30°C, inert atmosphere).
- Custom Blends: Tailoring specific water content, purity, and stabilizer profiles on demand (electronic, pharma, battery grades).

Tailored Solutions & Customization
- Grade Options: Ultra-pure (99.9%), Electronic, Pharma, Technical. Supplied per ISO/ASTM or customer-specific SOPs.
- Packaging: 200L drums, 1000L IBCs, ISO tanks, bulk shipment (UN rated, anti-static lined).
- Traceability: Each batch supplied with Certificate of Analysis (CoA), full trace chain.
- Delivery Lead Time: Standard 7-15 days (FOB/CIF/DDP), priority for pharma/electronics clients.
- On-site Support: Global partners for technical application guidance, hazardous material training, disposal and compliance consulting.
Application Scenarios & Case Studies
- Polymer Synthesis: Essential in polyacrylonitrile fiber & polysulfone membrane production; guarantees consistent viscosity, filtration, and elongation strength.
- Lithium Battery Electrolytes: Forms stable, conductive medium for new energy battery cell manufacturing; enhances cell durability and safety.
- API Intermediate Production: Used as reagent/solvent in active pharmaceutical synthesis (e.g., Nifedipine).
- Petrochemicals & Corrosion Protection: Slow evaporation rate and high polarity make it ideal in high-grade corrosion inhibitor and oilfield formulations.
- Electronics: Ultra-pure grades for LCD and semiconductor cleaning, advanced polymer resist stripping processes.
Challenge: Required ultra-low moisture NMF (<0.03%, certified to ISO 9001:2015, SEMI E49) for LCD panel process.
Result: Sincere Chemicals delivered 99.95% purity NMF with guaranteed moisture <300ppm, nickle-free packaging, and on-site process integration support. Annual defect rate reduced by 26% after upgrade.
Requirement: Consistent batch-to-batch N-Methylformamide quality for battery electrolyte production (EN 62282 conformity).
Impact: Custom drum packaging with inert gas blanketing provided. Enhanced shelf life and electrical stability reported by client's technical director.
Feedback: “Both process control and document traceability exceeded our multi-national chain audit!” — Project Engineer, Asian Pharma Group
Professional FAQ - N-Methylformamide Technical FAQ
Delivery Lead Time, Warranty & Customer Support
- Standard Delivery: 7 to 15 working days from confirmed order; express priority for pharma/electronics partners.
- Warranty: 12+ months from shipment with technical support guarantee and free analysis on charge disputes.
- Support: 24/7 expert technical support, global application consulting, MSDS/customs compliance advisory.
- After-sales: Replacement and on-site resolution of N-Methylformamide issues within 72 hours globally.
References & Industry Links
- [1] ISO 9001:2015 Quality Management Reference
- [2] Global Market Insights: N-Methylformamide Market Size 2023-2029
- [3] N-Methylformamide: Use & Safety in Pharmaceuticals, ResearchGate
- [4] ScienceDirect – N-Methylformamide Topics
- [5] Chemsynthesis Structure-Data – N-Methylformamide
- [6] ChemicalBook – NMF Industry Data (2024)
- [7] Industry Forum: Chemicals Technology
Post time: Aug . 02, 2025 12:40