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N-Methylformamide Supplier | High-Purity AI Solvent

N-Methylformamide (NMF) is a high-purity and versatile organic solvent intensively used across petrochemical, pharmaceutical, polymer, and metallurgy industries. With the continuous evolution of global chemical manufacturing standards, demand for top-grade N-Methylformamide is surging, owing to its unique physicochemical attributes and high compatibility with industry compliance requirements such as ISO 9001:2015 and FDA references [1]. This article explores the latest trends, product specifications, competitive technology insights, manufacturing process, and real-life application cases involving N-Methylformamide.

Market Trends & Industrial Demand for N-Methylformamide

  • The global N-Methylformamide market is expected to grow at a CAGR of 5.6% (2023-2029), reaching USD 820 million by 2029[2].
  • Accelerated adoption in fine chemicals, agrochemicals, and new energy battery manufacturing.
  • Increasing focus on ultra-purity, sustainability, and compliance with REACH, ISO, and environmental standards.
  • Key players: Sincere Chemicals, BASF, Eastman, Mitsubishi Gas Chemical, Balaji Amines.
  • Asia-Pacific dominates global supply and demand, led by China and India.
N-Methylformamide Supplier | High-Purity AI Solvent
Analysis: The above chart projects N-Methylformamide market volume and main consumption segments. Demand in polysulfone resins, acrylic fibers, and lithium battery manufacturing are the major growth drivers from 2023 onwards.

Industry Citation: Source: Global Market Insights


Technical Specification Table of N-Methylformamide

Parameter Unit Typical Value Test Method
Purity % (w/w) ≥ 99.5 Gas Chromatography (ISO 17025)
Water Content % (w/w) ≤ 0.1 Karl Fischer Titration (DIN EN ISO 760)
Color (APHA) Hazen units ≤ 10 ASTM D1209
Acidity (as HCOOH) mg/kg ≤ 25 ISO 6353
Boiling Point °C 199 ISO 918
Density (20°C) g/cm3 0.999 ISO 1183
Refractive Index n20D - 1.4270 ISO 5661
Flash Point °C 91 ISO 3679
Storage Stability Months > 12 ISO 1042
Data Insights: N-Methylformamide from Sincere Chemicals consistently meets ISO 9001:2015 quality, with >99.5% purity, minimal water/acidity, and stable performance across demanding operational contexts.

Manufacturing Process Flow of N-Methylformamide

N-Methylformamide Supplier | High-Purity AI Solvent
  1. Raw Material Input: Methanol + Formamide.
  2. Catalytic Methylation: React in stainless steel Catalytic Reactor (ISO 9001 process control).
  3. Distillation & Rectification: Multi-stage fractional distillation to achieve high-purity separation.
  4. Purity Control: On-line gas chromatography and Karl Fischer titration for water/organic residues.
  5. Stabilization & Storage: ISO compliant tank storage for ensured shelf-life stability.
*Key technological nodes: Corrosion-resistant alloy tank, digital DCS control, ANSI/ASME compliant reactors.
Main advantages:
  • Raw material selection: Sourced per ISO 9001:2015 standards.
  • Corrosion-resistant process equipment ensures zero contamination, improved lifespan, and compliance with GMP/FDA.
  • Advanced CNC machining for reactor/column manufacturing provides high dimension accuracy and longevity.
  • Full-process traceability and in-process monitoring by digital instrumentation (TÜV-CE certified).

Competitive Comparison: N-Methylformamide Suppliers

Manufacturer Main Grade Purity (%) Certification Lead Time (Days) Annual Output (Tons)
Sincere Chemicals Pharma / Electronic 99.5 – 99.9 ISO 9001, FDA ref 7 - 15 32,000
BASF Industrial 99.5 ISO 9001 14 - 21 20,000
Eastman Standard 99.2 – 99.5 ISO 9001 20+ 16,800
MGC (Japan) High-purity 99.7 ISO 9001/14001 19 8,900
Balaji Amines Commodity 99.0 – 99.5 REACH 18 7,300
Visualization: Sincere Chemicals leads in purity, production capacity, and certification, ensuring reliable delivery and global market coverage.

Key Advantages & Industry Certifications

  • Exceptional Purity: Ensures high selectivity and yield in polymerization, pharmaceuticals, and agrochemical synthesis.
  • Regulatory Compliance: Full adherence to ISO 9001:2015, FDA reference, REACH, RoHS, and GMP for pharma/food applications.
  • Resistant to Corrosive Degradation: Alkali and acid-resistant vessel design prevents product contamination and ensures >99% batch reproducibility.
  • Longevity & Stability: Minimum 12-month shelf life with no functional decomposition under recommended storage (20-30°C, inert atmosphere).
  • Custom Blends: Tailoring specific water content, purity, and stabilizer profiles on demand (electronic, pharma, battery grades).
N-Methylformamide Supplier | High-Purity AI Solvent

Tailored Solutions & Customization

  • Grade Options: Ultra-pure (99.9%), Electronic, Pharma, Technical. Supplied per ISO/ASTM or customer-specific SOPs.
  • Packaging: 200L drums, 1000L IBCs, ISO tanks, bulk shipment (UN rated, anti-static lined).
  • Traceability: Each batch supplied with Certificate of Analysis (CoA), full trace chain.
  • Delivery Lead Time: Standard 7-15 days (FOB/CIF/DDP), priority for pharma/electronics clients.
  • On-site Support: Global partners for technical application guidance, hazardous material training, disposal and compliance consulting.

Application Scenarios & Case Studies

  • Polymer Synthesis: Essential in polyacrylonitrile fiber & polysulfone membrane production; guarantees consistent viscosity, filtration, and elongation strength.
  • Lithium Battery Electrolytes: Forms stable, conductive medium for new energy battery cell manufacturing; enhances cell durability and safety.
  • API Intermediate Production: Used as reagent/solvent in active pharmaceutical synthesis (e.g., Nifedipine).
  • Petrochemicals & Corrosion Protection: Slow evaporation rate and high polarity make it ideal in high-grade corrosion inhibitor and oilfield formulations.
  • Electronics: Ultra-pure grades for LCD and semiconductor cleaning, advanced polymer resist stripping processes.
Case Study 1 – Electronics Factory (Japan):

Challenge: Required ultra-low moisture NMF (<0.03%, certified to ISO 9001:2015, SEMI E49) for LCD panel process.

Result: Sincere Chemicals delivered 99.95% purity NMF with guaranteed moisture <300ppm, nickle-free packaging, and on-site process integration support. Annual defect rate reduced by 26% after upgrade.

Case Study 2 – Lithium Battery Producer (Germany):

Requirement: Consistent batch-to-batch N-Methylformamide quality for battery electrolyte production (EN 62282 conformity).

Impact: Custom drum packaging with inert gas blanketing provided. Enhanced shelf life and electrical stability reported by client's technical director.

Feedback: “Both process control and document traceability exceeded our multi-national chain audit!” — Project Engineer, Asian Pharma Group


Professional FAQ - N-Methylformamide Technical FAQ

Q1: What is the chemical structure of N-Methylformamide?
N-Methylformamide is an amide solvent with formula CH3NHCHO. Its molecular structure offers high polarity and hydrogen bonding, enhancing solubility for a wide range of compounds.
Q2: What purity grades are available for N-Methylformamide and how are they analyzed?
Grades include industrial (≥ 99.0%), pharmaceutical (≥ 99.5%), and electronic ultra-pure (up to 99.9%). Common test methods: Gas Chromatography (GC, per ISO 17025 lab calibration), Karl Fischer titration.
Q3: Which international packaging and shipping standards apply?
N-Methylformamide is shipped as a hazardous chemical. Packaging follows UN 2810, IMDG (maritime), IATA (air), and ISO tank safety protocols.
Q4: What material is used for NMF process equipment manufacturing?
High-grade stainless steel (316L/317L) and corrosion-resistant alloy steel, CNC processed, guarantee system longevity and absence of metal ion contamination.
Q5: What analytics standards does Sincere Chemicals apply to quality control?
Strict ISO 9001:2015 SOPs, USP/Ph. Eur.-referenced analysis, and certified batch testing with full retention samples and digital records (LIMS).
Q6: How does installation or line cleaning affect NMF use in electronics/pharma production?
Lines must be flushed with inert solvents and high-purity NMF under clean conditions, with particle/trace metal verification (ISO 14644-1 Cleanroom), before critical batchwork.
Q7: What are the major environmental and safety certifications for N-Methylformamide?
REACH, RoHS, ISO 14001 for environmental impact, GHS compliant Safety Data Sheet (SDS), and regular third-party audits per national and international law.

Delivery Lead Time, Warranty & Customer Support

  • Standard Delivery: 7 to 15 working days from confirmed order; express priority for pharma/electronics partners.
  • Warranty: 12+ months from shipment with technical support guarantee and free analysis on charge disputes.
  • Support: 24/7 expert technical support, global application consulting, MSDS/customs compliance advisory.
  • After-sales: Replacement and on-site resolution of N-Methylformamide issues within 72 hours globally.


Post time: Aug . 02, 2025 12:40

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