Pentamethyldiethylenetriamine Toxicity Data

Understanding the safety profile of pentamethyldiethylenetriamine (CAS 3030 47 5) is crucial for its industrial applications in polyurethane production. As a leading chemical manufacturer, we provide comprehensive toxicity data for this important catalyst (CAS 3030 47 5) to ensure safe handling and compliance across all applications.

Pentamethyldiethylenetriamine Acute Toxicity

• Oral LD50- 580 mg/kg (rat) for CAS 3030 47 5
  • Dermal LD50 - >2000 mg/kg (rabbit) for pentamethyldiethylenetriamine
  • Inhalation LC50 - 1.2 mg/L (rat, 4h) for CAS 3030 47 5
  • Skin irritation - Moderate irritant (rabbit) for pentamethyldiethylenetriamine
  • Eye irritation - Severe irritant (rabbit) for CAS 3030 47 5
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3030 47 5 Chronic Exposure Effects

• Repeated dose toxicity - Liver/kidney effects at >50 mg/kg/day (90-day rat study)
  • Sensitization - Positive in guinea pig maximization test for pentamethyldiethylenetriamine
• • Reproductive toxicity - No adverse effects observed for CAS 3030 47 5 at <25 mg/kg/day
  • Mutagenicity - Negative in Ames test for pentamethyldiethylenetriamine
  • Carcinogenicity - Not classified (IARC, NTP) for CAS 3030 47 5

Pentamethyldiethylenetriamine Safety Handling

• PPE requirements - Chemical goggles, nitrile gloves for CAS 3030 47 5
  • Ventilation - Local exhaust required for pentamethyldiethylenetriaminehandling
  • Spill management - Inert absorbents for CAS 3030 47 5 containment
  • Storage conditions - Tightly sealed in cool, dry area for pentamethyldiethylenetriamine
  • Firefighting measures - Alcohol-resistant foam for CAS 3030 47 5 fires

3030 47 5 First Aid Measures

• Inhalation - Remove to fresh air for pentamethyldiethylenetriamineexposure
  • Skin contact - Wash immediately with soap/water for CAS 3030 47 5
  • Eye contact - Flush with water 15+ minutes for pentamethyldiethylenetriamine
  • Ingestion - Do NOT induce vomiting for CAS 3030 47 5
  • Medical attention - Required for all significant pentamethyldiethylenetriamine exposures
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Pentamethyldiethylenetriamine Regulatory Status

• REACH - Registered for CAS 3030 47 5
  • OSHA HazCom - Classified for pentamethyldiethylenetriamine
  • TSCA - Listed for CAS 3030 47 5
  • WHMIS - D2B classification for pentamethyldiethylenetriamine
  • GHS labeling - Required for CAS 3030 47 5shipments

Pentamethyldiethylenetriamine FAQs

Q: What are the primary industrial applications of pentamethyldiethylenetriamine?

A: Pentamethyldiethylenetriamine (CAS 3030-47-5) is widely used as a catalyst in polyurethane foam production, accelerating the reaction between isocyanates and polyols. It also functions as a ligand in metal complex synthesis and a curing agent in epoxy resin systems.

Q: How does the CAS 3030-47-5 compound differ from other amine catalysts in polyurethane formulations?

A: Compared to other amines, CAS 3030-47-5 offers balanced catalytic activity for both gel and blowing reactions in polyurethanes, enabling precise control over foam density and cell structure. Its tertiary amine structure reduces volatility, making it suitable for low-VOC applications.

Q: What safety precautions should be taken when handling 3030-47-5 in manufacturing?

A: 3030-47-5 is a corrosive liquid and may cause skin/eye irritation. Operators must wear chemical-resistant gloves and goggles; ensure good ventilation to avoid vapor inhalation. Store in sealed containers away from oxidizing agents and heat sources.

Q: Can pentamethyldiethylenetriamine (CAS 3030-47-5) be used in water-based formulations?

A: Yes, as pentamethyldiethylenetriamine is soluble in water, it can be incorporated into water-based coatings and adhesives. Its amine functionality helps adjust pH and improve film-forming properties, though compatibility with other additives should be tested for stability.

Q: What regulatory standards apply to 3030-47-5 in global chemical trade?

A: 3030-47-5 is listed under REACH (EC 1907/2006) and requires registration for use in the EU. In the U.S., it falls under OSHA’s Hazard Communication Standard (HCS), mandating SDS provision and worker training. Export compliance should also consider local regulations in Southeast Asia and North America.

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